PROFHILO is a high-concentration hyaluronic acid (HA) injectable designed primarily for bio-remodelling, not volume-filling. Alma Profhilo+2Proderma+2
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It uses 64 mg HA per 2 mL syringe, with both low and high molecular weight HA. Willow Tree Dental+2Proderma+2
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Unlike traditional HA fillers, it is not cross-linked with BDDE, which reduces risk of lumps and makes it more of a tissue-stimulator. Alma Profhilo+1
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It spreads under the skin (after injection) and stimulates the production of collagen and elastin, improving skin texture, tone, hydration and firmness. Wellness Laser Centre+1
Compared to Other Treatments
Here’s how PROFHILO compares to common alternatives in aesthetic medicine:
| Treatment |
Main Purpose |
How PROFHILO differs / advantages |
| Dermal fillers (HA fillers) |
Add volume, fill wrinkles/lines, enhance contours |
Fillers focus on adding structure or volume. PROFHILO instead focuses on improving skin quality, hydration and firmness rather than creating bulk. Byrdie+1
|
| Skin boosters / mesotherapy |
Injectables or very shallow injections to hydrate skin, improve glow |
Many skin-boosters provide hydration; PROFHILO has one of the highest concentrations of HA and adds a bio-stimulating facet (collagen/elastin stimulation) so has dual effect of hydration + remodelling. Two Face Aesthetics
|
| Botox / Neuromodulators |
Relax muscle activity (forehead lines, crow’s feet, etc) |
Botox addresses dynamic wrinkles through muscle relaxation. PROFHILO addresses skin laxity, texture, sagging by working on tissue/skin architecture rather than muscles. So they can complement each other rather than compete. |
| Laser / RF / Ultrasound skin tightening |
Stimulate collagen by heat or energy devices for skin lifting |
These are device-based treatments; PROFHILO is injectable, works from within the tissue. It may be less dramatic in lifting but has minimal downtime, and can be used where devices maybe less effective (e.g., thinner skin areas, neck, hands). |
| Traditional hydro-facials or chemical peels |
Surface exfoliation, superficial improvement in tone/texture |
These improve superficial skin layers; PROFHILO works deeper in the dermis/sub-dermal layers to remodel rather than just rejuvenate the surface. |
When might you choose PROFHILO?
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If the skin is showing early signs of laxity, thinning, dehydration, “crepey” texture, dull tone.
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If you want a more natural, subtle improvement (glow, tighter skin) rather than dramatic volume changes.
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If you have areas that are tricky for volume fillers (hands, neck, décolletage) where you want improved skin quality rather than bulk.
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If you prefer treatments with minimal downtime and fewer injection points (PROFHILO often uses fewer injection sites compared to large filling treatments) Genilo Derma Solutions+1
Things to Know / Limitations
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PROFHILO is not a filler: it will not give the same dramatic contouring or volume enhancement that a dedicated volumising filler will. rtwskin+1
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The effects are more gradual — you typically need two sessions spaced around 4 weeks apart for optimum results. Genilo Derma Solutions+1
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As with all injectables, results vary by individual, and lifestyle/skin condition still matter.
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Maintenance will be required (every ~6 months is commonly cited) for sustained effects. Allure
How to position it for your clients
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Emphasize “skin quality improvement” → hydration, firmness, elasticity, glow rather than “fill lines”.
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Use keywords like: skin bio-remodelling, internal skin hydration, improve skin texture and tone, subtle lift and tighten without volume bulk.
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Explain that it works very well alongside other treatments (fillers, RF, laser) in a comprehensive rejuvenation plan.
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Highlight minimal downtime, natural results, and suitability for multiple areas (face, neck, hands, arms).
